Honoring Michael Knowles, MD 2

On Friday, November 11th, Dr. Knowles will be honored with the Passion, Care and Dedication (PCD) Award at the PCD Foundation’s 20th Anniversary Celebration. This award recognizes his outstanding work in the education, diagnosis, prevention, treatment and cure of primary ciliary dyskinesia (PCD).

Join us in celebrating his many accomplishments by making a gift in his honor!

Michael Knowles, MD
Michael E. Hatcher Distinguished Professor of Medicine
Division of Pulmonary Disease and Critical Care Medicine
University of North Carolina, Chapel Hill


Dr. Knowles has been actively involved in translational research of genetic disorders of the airways for over 35 years.  His research interests include: genotype/phenotype of different mutations in CFTR; genetic modifiers of CF clinical disease phenotypes; development of diagnostic tests for Primary Ciliary Dyskinesia (PCD), including identification of “PCD-genes”; characterization of genotype/phenotype relations in PCD; and development of pharmacotherapy directed towards genetic diseases of the airways.


Dr. Knowles has previously been PI of 2 NIH sponsored research networks, including a U54-sponsored Rare Disease Consortium that included 8 North American sites, which is focused on PCD He is a co-founder of the International CF Gene Modifier Consortium, which has been active for >10 years. He has served on grant review committees for NIH study sections, and multiple voluntary health organizations (e.g., U.S. and Canadian CF Foundations; ATS; and PCD Foundation). Dr. Knowles has mentored over 23 postdoctoral trainees since 1987. He has published more than 280 peer reviewed manuscripts.